产品货号:
Z19771
中文名称:
LIMPII/SCARB2抗体
英文名称:
Anti-LIMPII/SCARB2 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-LIMPII/SCARB2 Antibody |
指标别名 | AMRF;CD36 antigen like 2;CD36L2;HLGP85;LGP85;LIMP II;limp2;LIMPII;Lysosome membrane protein 2;Lysosome membrane protein II;SCARB2;SR BII |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,IHC,IF,FCM,ELISA |
基因名称 | SCARB2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human Scavenging Receptor SRB2/SCARB2 recombinant protein (Position:E48-H357). |
实际分子量 | 80KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Lysosomal integral membrane protein 2 (LIMP-2) is a protein that in humans is encoded by the SCARB2 gene.The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes.Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment.The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction,deafness,and peripheral neuropathy.Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand,foot,and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16.Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4),also known as action myoclonus-renal failure syndrome (AMRF).Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Uniprot ID | Q14108 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
基因名全称 | scavenger receptor class B member 2 |
蛋白名全称 | Lysosome membrane protein 2 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Immunofluorescence (IF) 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells ELISA 1:100~1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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