产品货号:
Z19697
中文名称:
MALT1抗体
英文名称:
Anti-MALT1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-MALT1 Antibody |
指标别名 | MALT1;MLT;MLT1;Paracaspase |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | MALT1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human MALT1(809-824aa DEIPFSFSDRLRISEK). |
实际分子量 | 92KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | MALT1(Mucosa-associated lymphoid tissue lymphoma translocation protein 1),also called MLT or PARACASPASE,is a protein that in humans is encoded by the MALT1 gene.This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3(also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas.Dierlamm et al.(1999) and Akagi et al.(1999) mapped the MALT1 gene to chromosome 18q21.Using mouse models,Ruland et al.(2003) demonstrated that MALT1 is essential for T-cell activation,proliferation,and IL2 production in response to T-cell receptor ligation and strictly required for signal-specific NF-kappa-B(NFKB) activation induced by the T-cell receptor but not TNF-alpha or IL1 signaling.MALT1 operates downstream of BCL10,controls the catalytic activity of the canonical I-kappa-B kinase complex,and regulates the signaling of JNK and p38 MAP kinases. |
Uniprot ID | Q9UDY8 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | mucosa associated lymphoid tissue lymphoma translocation gene 1 |
蛋白名全称 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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