产品货号：
Z19630
中文名称：
KREMEN1抗体
英文名称：
Anti-KREMEN1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-KREMEN1 Antibody |
| 指标别名 | KRM1;KREMEN;KRM1;Kremen protein 1;Dickkopf receptor |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | KREMEN1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Rabbit polyclonal KREMEN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KREMEN1.The immunogen is located within the last 50 amino acids of KREMEN1. |
| 计算分子量 | 52kDa |
| 成分 | KREMEN1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | KREMEN1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle,WSC and CUB domains and an intracellular region without any conserved motifs.Kremens bind a subset of the secreted Dickkopf proteins (Dkk 1,2,and 4) with high affinity to modulate the canonical Wnt signaling pathway that is transduced by the ternary receptor complex composed of Wnt,Frizzled,and the LDL receptor related protein 5/6 (LRP5/6) coreceptor.KREMEN1 is a receptor for the Dickkopf protein which blocks Wnt/beta catenin signaling.It is necessary to ensure normal spatial and temporal patterns of Wnt activity during developmental processes. |
| Uniprot ID | Q96MU8 |
| 基因名全称 | Kringle containing transmembrane protein 1 |
| 蛋白名全称 | Kringle containing transmembrane protein 1 |
| 推荐稀释比 | KREMEN1 antibody can be used for detection of KREMEN1 by Western blot at 0.125 ～ 0.25μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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