产品货号：
Z19627
中文名称：
KPNA6抗体
英文名称：
Anti-KPNA6 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-KPNA6 Antibody |
| 指标别名 | Importin subunit alpha 7;IPOA7;Karyopherin subunit alpha 6;KPNA6 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IF |
| 基因名称 | KPNA6 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | KPNA6 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human KPNA6.The immunogen is located within amino acids 70 - 120 of KPNA6. |
| 计算分子量 | 60kDa |
| 成分 | KPNA6 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | KPNA6 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Karyopherin,a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits,is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring,Ran-dependent mechanism.The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm,while the beta subunit accumulates at the NPC.KPNA6 belongs to a subfamily within the KPNA family that also includes IPOA5&6.Down-regulation of KPNA6 by RNAi expression in HeLa cells strongly inhibited cell proliferation,possibly due to blocking the nuclear import of specific factors essential for cell growth and proliferation.KPNA6 also interacts with the Rev protein of HIV-1 and promote its nuclear import. |
| Uniprot ID | O60684 |
| 基因名全称 | Karyopherin alpha 6 (importin alpha 7) |
| 蛋白名全称 | Karyopherin alpha 6 (importin alpha 7) |
| 推荐稀释比 | KPNA6 antibody can be used for detection of KPNA6 by Western blot at 1μg/mL.Antibody can also be used for immunofluorescence starting at 20μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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