产品货号：
Z19583
中文名称：
LAMP2抗体
英文名称：
Anti-LAMP2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-LAMP2 Antibody |
| 指标别名 | CD107b;Cell and organelle markers;LAMP 2;LAMP2;LAMPB;LGP110;Lysosome Marker |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,ICC,IHC |
| 基因名称 | LAMP2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | LAMP-2 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human LAMP-2.The immunogen is located within the last 50 amino acids of LAMP-2. |
| 计算分子量 | 46kDa |
| 成分 | LAMP-2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | LAMP-2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Autophagy,the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells.It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components and is negatively regulated by TOR (Target of rapamycin).LAMP-2,a highly glycosylated protein associated with the lysosome,has recently been shown to be important in autophagy as mice deficient in this protein failed to convert autophagic vacuoles into vacuoles leading to impaired degradation of long-lived proteins.This correlates with the finding that human LAMP-2 deficiency causing Danon's disease is associated with the accumulation of autophagic material in striated myocytes.LAMP-2 exists in multiple isoforms. |
| Uniprot ID | P17047 |
| 基因名全称 | Lysosomal-associated membrane protein 2 |
| 蛋白名全称 | Lysosomal-associated membrane protein 2 |
| 推荐稀释比 | LAMP-2 antibody can be used for the detection of LAMP-2 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL and immunohistochemistry starting at 5μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in mouse samples and Immunocytochemistry in human samples.All other applications and species not yet tested. |
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