产品货号：
Z19567
中文名称：
JMJD1A/KDM3A抗体
英文名称：
Anti-JMJD1A/KDM3A antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-JMJD1A/KDM3A antibody |
| 指标别名 | JHDM2A;JHMD2A;JMJD1;JMJD1A;KDM3A;KIAA0742;lysine (K) demethylase 3A;Lysine specific demethylase 3A;TSGA |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,ICC/IF,IP,ELISA |
| 基因名称 | KDM3A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human KDM3A recombinant protein (Position:T4-T359). |
| 实际分子量 | 150KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The jumonji domain containing 1A protein (JMJD1A) was originally discovered as a testes specific gene,but has been found to be expressed in numerous tissues.JMJD1A is a histone demethylase and specifically demethylates mono- and dimethyl-H3K9.It has also been found to be a novel interaction partner with ER71,a transcription factor expressed in the testes of adult mice and during embryogenesis.JMJD1A is also a downstream gene of STAT3,a protein that has been found to be important in the maintenance of mouse embryonic stem (mES) cells,and decreased JMJD1A expression correlated with the differentiation of cultured mES cells following the removal of the cytokine LIF.These findings suggest that JMJD1A might be a critical signaling molecule underlying the maintenance of pluripotency in embryonic stem cells.At least two isoforms of JMJD1A are known to exist. |
| Uniprot ID | Q9Y4C1 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | lysine demethylase 3A |
| 蛋白名全称 | Lysine (K)-specific demethylase 3A |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 ImmunoPrecipitation (IP) 1:50 Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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