产品货号：
Z19562
中文名称：
JMJD3/KDM6B抗体
英文名称：
Anti-JMJD3/KDM6B Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-JMJD3/KDM6B Antibody |
| 指标别名 | lysine demethylase 6B;JMJD3;NEDCFSA;KDM6B |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | KDM6B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Anti-JMJD3 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human JMJD3.The immunogen is located within amino acids 1370-1420 of JMJD3. |
| 计算分子量 | 177kDa |
| 成分 | JMJD3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | JMJD3 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The Jumonji domain-containing protein 3 (JMJD3) functions as a trimethylation-specific demethylase,converting the trimethylated histone H3 Lys27 residue to the dimethylated form,and is thought to also function as a transcriptional repressor.JMJD3 plays a central role in regulation of posterior development,by regulating HOX gene expression.It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.JMJD3 can also interact with and demethylate p53,resulting in its stabilization and localization to the nucleus in mouse embryo fibroblasts during neural stem cell differentiation. |
| Uniprot ID | O15054 |
| 基因名全称 | Lysine (K)-specific demethylase 6B |
| 蛋白名全称 | Lysine (K)-specific demethylase 6B |
| 推荐稀释比 | WB:0.25～4μg/mL;ICC:2.5μg/mL;IF:20μg/mL.Antibody validated:Western Blot in human,mouse and rat samples;Immunocytochemistry in human samples;Immunofluorescence in human samples.All other applications and species not yet tested. |
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