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产品目录

KU70/XRCC6抗体图片
产品货号:
Z19495
中文名称:
KU70/XRCC6抗体
英文名称:
Anti-KU70/XRCC6 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-KU70/XRCC6 Antibody
指标别名5 dRP lyase Ku70;70kDa subunit of Ku antigen;CTC75;CTCBF;DNA repair protein XRCC6;G22P1;KU70;ML8;Thyroid lupus autoantigen;TLAA;XRCC6
克隆性Polyclonal
检验物种human
应用范围WB,IHC,ICC
基因名称XRCC6
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the C-terminus of human Ku70(530-545aa YPPDYNPEGKVTKRKH).
实际分子量70KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料XRCC6(X-Ray Repair,Complementing Defective,In Chinese Hamster,6),also called Ku70,G22P1 or TLAA,is a protein that in humans,is encoded by the XRCC6 gene.In addition,the XRCC6 gene encodes subunit p70 of the p70/p80 autoantigen which consists of 2 proteins of molecular mass of approximately 70,000 and 80,000 daltons that dimerize to form a 10 S DNA-binding complex.The XRCC6 gene is mapped to 22q13.2.XRCC6 and Mre11 are differentially expressed during meiosis.XRCC6 interacts with Baxa,a mediator of mitochondrial-dependent apoptosis.Disruption of both FANCC and XRCC6 suppressed sensitivity to crosslinking agents,diminished chromosome breaks,and reversed defective homologous recombination.Ku70 binds directly to free DNA ends,committing them to NHEJ repair.In early meiotic prophase,however,when meiotic recombination is most probably initiated,Mre11 was abundant,whereas XRCC6 was not detectable.
Uniprot IDP12956
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称X-ray repair complementing defective repair in Chinese hamster cells 6
蛋白名全称X-ray repair cross-complementing protein 6
推荐稀释比
Western blot (WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
Immunocytochemistry 1:50~400
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:KU70/XRCC6抗体KU70抗体XRCC6多抗Anti-KU70/XRCC6 Antibody
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