产品货号：
Z19474
中文名称：
KINDLIN3/FERMT3抗体
英文名称：
Anti-KINDLIN3/FERMT3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-KINDLIN3/FERMT3 Antibody |
| 指标别名 | URP2;KIND3;MIG-2;MIG2B;URP2SF;UNC112C;URP2;Fermitin family homolog 3;Kindlin-3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | FERMT3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | KINDLIN3 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of the human KINDLIN3.The immunogen is located within the last 50 amino acids of KINDLIN3. |
| 计算分子量 | 76kDa |
| 成分 | KINDLIN3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | KINDLIN3 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The three KINDLINs are a novel family of focal adhesion proteins,localizing to integrin adhesion sites.The KINDLIN proteins are composed of a centrally located FERM domain interrupted by a pleckstrin homology (PH) domain.KINDLIN1 and KINDLIN2 have been shown to play an essential role in integrin-mediated adhesion and spreading.In contrast to the widely expressed KINDLIN1 and KINDLIN2,KINDLIN3 is restricted to hematopoietic cells and is particularly abundant in megakaryocytes and platelets.Several reports describe a transcriptional misregulation of KINDLINs in various types of cancer.A recent study demonstrates that KINDLIN3 is essential for platelet integrin activation and subsequent integrin outside-in signaling,suggesting it may serve as a potential target for the design of therapeutics aimed at specifically disrupting integrin activation in platelets and leukocytes. |
| Uniprot ID | Q86UX7 |
| 基因名全称 | Fermitin family homolog 3 (Drosophila) |
| 蛋白名全称 | Fermitin family homolog 3 (Drosophila) |
| 推荐稀释比 | KINDLIN3 antibody can be used for detection of KINDLIN3 by Western blot at 1 and 2μg/mL.Antibody validated:Western Blot in rat samples.All other applications and species not yet tested. |
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