产品货号：
Z19416
中文名称：
JAGN1抗体
英文名称：
Anti-JAGN1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-JAGN1 Antibody |
| 指标别名 | Jagunal homolog 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | JAGN1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | JAGN1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human JAGN1.The immunogen is located within the last 50 amino acids of JAGN1. |
| 计算分子量 | 21kDa |
| 成分 | JAGN1 antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | JAGN1 antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | JAGN1 is the human ortholog of a gene originally identified in Drosophila melanogaster.It is a transmembrane protein that functions in the early secretory pathway and is necessary for neutrophil differentiation and survival.Individuals with mutations in the JAGN1 gene causes aberrant myeloid cell homeostasis and severe congenital neutropenia (SCN) (1).JAGN1-mutant granulocytes are characterized by ultrastructural defects,aberrant N-glycosylation of multiple proteins,and increased apoptosis (1).Mice lacking this gene could not mount and efficient neutrophil-dependent immune response to a human fungal pathogen (2). |
| Uniprot ID | Q8N5M9 |
| 基因名全称 | Jagunal homolog 1 |
| 蛋白名全称 | Jagunal homolog 1 |
| 推荐稀释比 | JAGN1 antibody can be used for detection of JAGN1 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.Antibody validated:Western Blot in human samples and Immunohistochemistry in rat samples.All other applications and species not yet tested. |
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