产品货号：
Z19406
中文名称：
JAK1抗体
英文名称：
Anti-JAK1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-JAK1 Antibody |
| 指标别名 | Janus kinase 1;AIIDEA;JAK1B;JTK3;JAK1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | JAK1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human JAK1 (78-115aa FALYDENTKLWYAPNRTITVDDKMSLRLHYRMRFYFTN),different from the related mouse sequence by three amino acids. |
| 实际分子量 | 133KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | JAK1 (JANUS KINASE 1) is a human tyrosine kinase protein essential for signaling for certain type I and type II cytokines.It is a member of a new class of PTKs that are a large family of proteins characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain--hence the name Janus.The JAK1 gene is mapped to 1p31.3.JAK1 is also important for transducing a signal by type I (IFN-α/β) and type II (IFN-γ) interferons,and members of the IL-10 family via type II cytokine receptors.Additionally,Jak1 plays a critical role in initiating responses to multiple major cytokine receptor families.Loss of Jak1 is lethal in neonatal mice,possibly due to difficulties suckling.Expression of JAK1 in cancer cells enables individual cells to contract,potentially allowing them to escape their tumor and metastasize to other parts of the body. |
| Uniprot ID | P23458 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
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