产品货号：
Z19382
中文名称：
LIG4抗体
英文名称：
Anti-LIG4 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-LIG4 Antibody |
| 指标别名 | DNA ligase 4;DNA ligase IV;LIG4;ligase IV;DNA;ATP dependent |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | LIG4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from the Internal region of human DNA Ligase IV.at AA rangle:560-640 |
| 计算分子量 | 104KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | Immunogen affinity purified |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | DNA ligase 4 is an enzyme that in humans is encoded by the LIG4 gene.The protein encoded by this gene is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction.This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ).This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4),and further interacts with the DNA-dependent protein kinase (DNA-PK).Both XRCC4 and DNA-PK are known to be required for NHEJ.The crystal structure of the complex formed by this protein and XRCC4 has been resolved.Defects in this gene are the cause of LIG4 syndrome.Alternatively spliced transcript variants encoding the same protein have been observed. |
| Uniprot ID | P49917 |
| 基因名全称 | DNA ligase 4 |
| 推荐稀释比 | WB,1:500～1:2000 |
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