产品货号:
Z19252
中文名称:
KDM3B抗体
英文名称:
Anti-KDM3B Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-KDM3B Antibody |
指标别名 | 5qNCA,C5orf7,JHDM2B,JMJD1B,KDM3B,KIAA1082,lysine (K) demethylase 3B,Lysine specific demethylase 3B,NET22,Nuclear protein 5qNCA |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | KDM3B |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | JMJD1B antibody was raised against a 20 amino acid synthetic peptide from near the center of human JMJD1B.The immunogen is located within amino acids 1050 - 1100 of JMJD1B. |
计算分子量 | 192kDa |
成分 | JMJD1B Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | JMJD1B Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | The jumonji domain containing 1B protein (JMJD1B) was originally discovered as a candidate for the myeloid leukemia tumor suppressor gene.Besides CD34+ cells and acute myeloid leukemia (AML) cell lines,JMJD1B mRNA is highly expressed in liver,heart,kidney,skeletal muscle,and placenta tissues.The JMJD1B gene is localized to a region of chromosome 5q31,which is frequently deleted in myeloid leukemias and myelodysplasias and expression of JMJD1B in a del(5q) cell line results in suppression of clonogenic growth suggesting that JMJD1B may function as a tumor suppressor.In contrast,JMJD1B gene copy number and mRNA expression level was increased in several non-small cell lung cancers indicating that the role of JMJD1B in cancer formation and progression is more complex than originally postulated.At least three isoforms of JMJD1B are known to exist. |
Uniprot ID | Q7LBC6 |
基因名全称 | Lysine (K)-specific demethylase 3B |
蛋白名全称 | Lysine (K)-specific demethylase 3B |
推荐稀释比 | JMJD1B antibody can be used for detection of JMJD1B by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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