产品货号:
Z19245
中文名称:
KDM4A抗体
英文名称:
Anti-KDM4A Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-KDM4A Antibody |
| 指标别名 | JHDM3A;JMJD2;JMJD2A;KDM4A;KIAA0677;lysine (K) demethylase 4A;Lysine specific demethylase 4A |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | KDM4A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | JMJD2A antibody was raised against a 14 amino acid synthetic peptide from near the center of human JMJD2A.The immunogen is located within amino acids 340 - 390 of JMJD2A. |
| 计算分子量 | 121kDa |
| 成分 | JMJD2A Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | JMJD2A Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
| 背景资料 | Members of the Jumonji domain 2 (JMJD2) family contain a JmjN domain,a JmjC domain,a JD2H domain,two TUDOR domains,and two PHD-type zinc fingers.The first member of this group,JMJD2A,is widely expressed in human tissues and cell lines and functions as a trimethylation-specific demethylase,converting specific trimethylated histone residues to the dimethylated form,and as a transcriptional repressor.JMJD2A can also form a complex with the androgen receptor (AR),a transcription factor that is pivotal for the development of prostate cancer.Overexpression of JMJD2A stimulates AR function and this stimulation is dependent on JMJD2A catalytic activity,suggesting that JMJD2A might be a critical protein with roles in cell proliferation and oncogenesis. |
| Uniprot ID | O75164 |
| 基因名全称 | Lysine (K)-specific demethylase 4A |
| 蛋白名全称 | Lysine (K)-specific demethylase 4A |
| 推荐稀释比 | JMJD2A antibody can be used for detection of JMJD2A by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.Antibody validated:Western Blot in rat samples and Immunohistochemistry in rat samples.All other applications and species not yet tested. |
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