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所在位置:所有产品 > 抗体抗原 > 一抗 > Lamin A/C抗体
Lamin A/C抗体图片
产品货号:
Z19221
中文名称:
Lamin A/C抗体
英文名称:
Anti-Lamin A/C Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-Lamin A/C Antibody
指标别名70kDa lamin;CDCD1;CDDC;CMD1A;CMT2B1;EMD2;FPL;FPLD;HGPS;IDC;lamin A;lamin A/C;LDP1;LFP;LGMD1B;LMN1;LMNA;LMNC;Prelamin A/C;PRO1;progerin
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB,IHC,IF,FCM,ICC/IF
基因名称LMNA
抗体来源Rabbit
抗体类型IgG
免疫原E.coli-derived human Lamin A/C recombinant protein (Position:Y481-Y646).Human Lamin A/C shares 90% and 92% amino acid (aa) sequence identity with mouse and rat Lamin A/C,respectively.
计算分子量74KD
实际分子量74KD,63KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Lamins are structural protein components of the nuclear lamina,a protein network underlying the inner nuclear membrane that determines nuclear shape and size.There are three types of lamins,A,B and C.The lamin A/C (LMNA) gene contains 12 exons.Alternative splicing within exon 10 gives rise to two different mRNAs that code for pre-lamin A and lamin C.Lamin A/C is mapped to 1q21.2-q21.3 and mutations in this gene cause a variety of human diseases including Emery-Dreifuss muscular dystrophy,dilated cardiomyopathy,and Hutchinson-Gilford progeria syndrome.Lamin A/C deficiency is thus associated with both defective nuclear mechanics and impaired mechanically activated gene transcription.
Uniprot IDP02545
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称lamin A/C
蛋白名全称Prelamin-A/C
推荐稀释比
Western blot (WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
Immunofluorescence (IF) 1:50~400
Immunocytochemistry/Immunofluorescence(ICC/IF) 1:50~400
Flow cytometry (FCM) 1~3μg/1×106 cells
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:Lamin A/C抗体Lamin A抗体C多抗Anti-Lamin A/C Antibody
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