产品货号：
Z19175
中文名称：
IRGC抗体
英文名称：
Anti-IRGC Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IRGC Antibody |
| 指标别名 | CINEMA;Iigp5;Interferon inducible GTPase 5;IRGC;IRGC1;R30953_1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | IRGC |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | IRGC antibody was raised against a 12 amino acid synthetic peptide near the carboxy terminus of human IRGC.The immunogen is located within the last 50 amino acids of IRGC. |
| 计算分子量 | 50kDa |
| 成分 | IRGC Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | IRGC Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Immunity-related GTPases (IRG) (also known as p47 GTPases) are a family of GTPase proteins found in vertebrates,which play critical roles in mediating innate resistance to intracellular pathogens.IRG genes have been found in a number of mammals and lower species including mice,rats,zebrafish and humans.Most of the mouse genes contain interferon-stimulated response elements which mediate transcriptional activation by IFNs.In humans,only two IRG genes have been found:human IRGC encodes a full-length IRG protein that,like the mouse homologue,is constitutively expressed in testis,while human IRGM encodes a considerably truncated protein that is constitutively expressed in cultured cells including some macrophage cell lines.As the two human genes IRGC and IRGM are not subject to IFN control,it has been suggested that the host resistance mechanism supported by IRG proteins in the mouse is lacking in humans. |
| Uniprot ID | Q6NXR0 |
| 基因名全称 | Immunity-related GTPase family,cinema |
| 蛋白名全称 | Immunity-related GTPase family,cinema |
| 推荐稀释比 | IRGC antibody can be used for detection of IRGC by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunocytochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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