产品货号：
Z19173
中文名称：
IRGM抗体
英文名称：
Anti-IRGM Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IRGM Antibody |
| 指标别名 | IFI1;IRGM1;LRG47;LRG-47;IFI1;Immunity-related GTPase family M protein;Immunity-related GTPase family M protein 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | IRGM |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | IRGM antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of the human IRGM.The immunogen is located within amino acids 30 - 80 of IRGM. |
| 计算分子量 | 20kDa |
| 成分 | IRGM Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | IRGM Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Autophagy,the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells.It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components.Two of the strongest hits implicate genes IRGM and ATG16L1,which encode proteins thought to be critical to the autophagy pathway and being significantly associated with Crohn's disease.IRGM induces autophagy and generates large autolysosomal organelles as a mechanism for the elimination of intracellular Mycobacterium tuberculosis.In mouse,IRGM belongs to a family of gamma-interferon-induced GTP-binding proteins of approximately 48kDa that also includes IRGM2 and IRGM3;this antibody may also recognize these proteins. |
| Uniprot ID | A1A4Y4 |
| 基因名全称 | Immunity-related GTPase family,M |
| 蛋白名全称 | Immunity-related GTPase family,M |
| 推荐稀释比 | IRGM antibody can be used for detection of IRGM by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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