产品货号：
Z19081
中文名称：
ITPR1抗体
英文名称：
Anti-ITPR1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ITPR1 Antibody |
| 指标别名 | INSP3R1;IP3 receptor isoform 1;IP3R;IP3R 1;IP3R1;ITPR1;SCA15;SCA16;Type 1 InsP3 receptor |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | ITPR1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human IP3 receptor recombinant protein (Position:A2411-A2758).Human IP3 receptor shares 98% and 97% amino acid (aa) sequences identity with mouse and rat IP3 receptor,respectively. |
| 实际分子量 | 290KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Inositol 1,4,5-trisphosphate receptor type 1,also known as IP3R or IP3R1,is a protein that in humans is encoded by the ITPR1 gene.It is mapped to 3p26.1.The product of the ITPR1 gene is predominantly enriched in cerebellar Purkinje cells but is also concentrated in neurons in the hippocampal CA1 region,caudate-putamen,and cerebral cortex.The ITPR1 gene encodes the inositol 1,4,5-triphosphate(IP3) receptor,an intracellular IP3-gated calcium channel that modulates intracellular calcium signaling.Upon stimulation by inositol 1,4,5-trisphosphate,this receptor mediates calcium release from the endoplasmic reticulum.Mutations in ITPR1 cause spinocerebellar ataxia type 15,a disease associated with an heterogeneous group of cerebellar disorders. |
| Uniprot ID | Q14643 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | inositol 1,4,5-trisphosphate receptor,type 1 |
| 蛋白名全称 | Inositol 1,4,5-trisphosphate receptor type 1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：ITPR1抗体，ITPR1多抗，Anti-ITPR1 Antibody