产品货号：
Z19079
中文名称：
ITPR3抗体
英文名称：
Anti-ITPR3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ITPR3 Antibody |
| 指标别名 | inositol 1;4;5-trisphosphate receptor type 3;IP3R;IP3R3;ITPR3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | ITPR3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human ITPR3 (70-95aa QYWKAKQTKQDKEKIADVVLLQKLQH),identical to the related mouse and rat sequences. |
| 实际分子量 | 270～300KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ITPR3 encodes a receptor for inositol 1,4,5-trisphosphate,a second messenger that mediates the release of intracellular calcium.The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus.Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.ITP3 channels serve an important role in the taste transduction pathway of sweet,bitter and umami tastes the gustatory system.ITP3 channels allow the flow of Calcium out of the endoplasmic reticulum in response to IP3.Calcium cations result in the activation of TRPM5 which leads to a depolarisation generating potential and an action potential. |
| Uniprot ID | Q14573 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | inositol 1,4,5-trisphosphate receptor,type 3 |
| 蛋白名全称 | Inositol 1,4,5-trisphosphate receptor type 3 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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