产品货号：
Z19042
中文名称：
HSF1抗体
英文名称：
Anti-HSF1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HSF1 Antibody |
| 指标别名 | Heat shock factor protein 1;HSF 1;HSF1;HSTF 1;HSTF1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,FCM |
| 基因名称 | HSF1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human HSF1 (KQLVHYTAQPLFLLDP). |
| 实际分子量 | 80KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | HSF1(HEAT-SHOCK TRANSCRIPTION FACTOR 1),also called HEAT-SHOCK FACTOR 1,is a protein that in humans is encoded by the HSF1 gene.The product of HSF1 gene is a heat-shock transcription factor.The International Radiation Hybrid Mapping Consortium maps the HSF1 gene to chromosome 8.HSF1 exists as an inactive monomer in a complex with Hsp40/Hsp70 and Hsp90.Upon stress,such as elevated temperature,HSF1 is released from the chaperone complex and trimerizes.HSF1 is then transported into the nucleus where it is hyperphosphorylated and binds to DNA containing heat shock elements.HSF1's target genes include major inducible heat shock proteins such as Hsp72,and interestingly,noncoding RNA within Satellite III repeat regions.In a novel in vitro system human HSF1 can be activated by nonnative protein,heat,and geldanamycin.HSR1 is constitutively expressed in human and rodent cells and its homologs are functionally interchangeable.Furthermore,Hsf1-deficient mice had a longer free-running period than wildtype littermates. |
| Uniprot ID | Q00613 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | heat shock transcription factor 1 |
| 蛋白名全称 | Heat shock factor protein 1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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