产品货号:
Z19018
中文名称:
KCNA5抗体
英文名称:
Anti-KCNA5 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-KCNA5 Antibody |
指标别名 | ATFB7;HCK1;HK2;HPCN1;KCNA5;KV1.5;PCN1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC |
基因名称 | KCNA5 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human KCNA5 (583-613aa LEKCNVKAKSNVDLRRSLYALCLDTSRETDL),different from the related mouse and rat sequences by two amino acids. |
实际分子量 | 67KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Potassium voltage-gated channel,shaker-related subfamily,member 5,also known as KCNA5 or Kv1.5,is a protein that in humans is encoded by the KCNA5 gene.Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints.KCNA5 encodes a member of the potassium channel,voltage-gated,shaker-related subfamily.This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment.It belongs to the delayed rectifier class,the function of which could restore the resting membrane potential of beta cells after depolarization,thereby contributing to the regulation of insulin secretion.This gene is intronless,and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12.Mutations in this gene have been related to both atrial fibrillation and sudden cardiac death.KCNA5 are also key players in pulmonary vascular function,where they play a role in setting the resting membrane potential and its involvement during hypoxic pulmonary vasoconstriction. |
Uniprot ID | P22460 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | potassium channel,voltage gated shaker related subfamily A,member 5 |
蛋白名全称 | Potassium voltage-gated channel subfamily A member 5 |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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