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所在位置:所有产品 > 抗体抗原 > 一抗 > IRE1/ERN1抗体
IRE1/ERN1抗体图片
产品货号:
Z18967
中文名称:
IRE1/ERN1抗体
英文名称:
Anti-IRE1/ERN1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-IRE1/ERN1 Antibody
指标别名ERN1;hIRE1p;Inositol requiring protein 1;IRE1;Ire1 alpha;IRE1;ERN1;IRE1P;IRE1α
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB,ICC/IF,FCM,ELISA
基因名称ERN1
抗体来源Rabbit
抗体类型IgG
免疫原E.coli-derived human IRE1 recombinant protein (Position:R158-L280).
实际分子量110KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料The serine/threonine-protein kinase/endoribonuclease inositol-requiring enzyme 1 (IRE1) is an enzyme that in humans is encoded by the ERN1 gene.This gene encodes the transmembrane protein kinase inositol-requiring enzyme 1.The encoded protein contains two functional catalytic domains,a serine/threonine-protein kinase domain and an endoribonuclease domain.This protein functions as a sensor of unfolded proteins in the endoplasmic reticulum (ER) and triggers an intracellular signaling pathway termed the unfolded protein response (UPR).The UPR is an ER stress response that is conserved from yeast to mammals and activates genes involved in degrading misfolded proteins,regulating protein synthesis and activating molecular chaperones.This protein specifically mediates the splicing and activation of the stress response transcription factor X-box binding protein 1.
Uniprot IDO75460
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
推荐稀释比
Western blot(WB) 1:500~2000
(ELISA): 1:100~1000
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400
Flow cytometry (FCM) 1~3μg/1×106 cells

相关搜索:IRE1/ERN1抗体IRE1抗体ERN1多抗Anti-IRE1/ERN1 Antibody
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