产品货号：
Z18921
中文名称：
IkB Beta/NFKBIB抗体
英文名称：
Anti-IkB Beta/NFKBIB Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IkB Beta/NFKBIB Antibody |
| 指标别名 | I kappa B beta;IkappaBbeta;IkB B;IkB beta;IKBB;NF kappa B inhibitor beta;NF kappa BIB;NFKBIB;TR interacting protein 9;TRIP 9;TRIP9 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | NFKBIB |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human IKB beta recombinant protein (Position:E56-E237).Human IKB beta shares 82% and 80% amino acid (aa) sequence identity with mouse and rat IKB beta,respectively. |
| 实际分子量 | 48KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | NF-kappa-B inhibitor beta,also known as IKBB or TRIP9,is a protein that in humans is encoded by the NFKBIB gene.The protein encoded by this gene belongs to the NF-kappa-B inhibitor family,which inhibit NF-kappa-B by complexing with,and trapping it in the cytoplasm.This gene is mapped to 19q13.2.It has been found that in vivo,NFKBIB serves both to inhibit and to facilitate the inflammatory response.NFKBIB degradation releases NF-kappa-B dimers,which upregulate proinflammatory target genes such as TNF-alpha.Surprisingly,absence of NFKBIB results in a dramatic reduction of TNF-alpha in response to lipopolysaccharide,even though activation of NF-kappa-B is normal. |
| Uniprot ID | Q15653 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor,beta |
| 蛋白名全称 | NF-kappa-B inhibitor beta |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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