产品货号：
Z18832
中文名称：
IKK Alpha/CHUK抗体
英文名称：
Anti-IKK Alpha/CHUK Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IKK Alpha/CHUK Antibody |
| 指标别名 | component of inhibitor of nuclear factor kappa B kinase complex;IKBKA;IKK-alpha;IKK1;IKKA;NFKBIKA;TCF16;CHUK |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | CHUK |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | IKK alpha antibody was raised against a 19 amino acid peptide near the carboxy terminus of human IKK alpha.The immunogen is located within the last 50 amino acids of IKK alpha. |
| 计算分子量 | 85kDa |
| 成分 | IKK alpha Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | IKK alpha Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Nuclear factor kappa B (NF-百B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses.NF-百B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1,TNFa,and bacteria product LPS.NF-百B is associated with I百B proteins in the cell cytoplasm,which inhibit NF-百B activity.The long-sought I百B kinase (IKK),which phosphorylates I百B,and mediates I百B degradation and NF-百B activation,was recently identified by several laboratories.IKK is a serine protein kinase,and the IKK complex contains alpha and beta subunits (IKK汐and IKK汕).IKK汐and IKK汕interact with each other and both are essential for the NF-百B activation.IKK汐specifically phosphorylates IkB-alpha.IKK汐is expressed in variety of human tissues. |
| Uniprot ID | O15111 |
| 基因名全称 | Conserved helix-loop-helix ubiquitous kinase |
| 蛋白名全称 | Conserved helix-loop-helix ubiquitous kinase |
| 推荐稀释比 | IKK alpha can be used for detection of IKK alpha by Western blot at 1μg/mL.An 85kDa band should be detected.Antibody can also be used for immunocytochemistry starting at 1μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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