产品货号：
Z18660
中文名称：
IL28RA/IFNLR1抗体
英文名称：
Anti-IL28RA/IFNLR1 Antibody (Center)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IL28RA/IFNLR1 Antibody (Center) |
| 指标别名 | Interferon lambda receptor 1;IFN-lambda receptor 1;IFN-lambda-R1;Cytokine receptor class-II member 12;Cytokine receptor family 2 member 12;CRF2-12;Interleukin-28 receptor subunit alpha;IL-28 receptor subunit alpha;IL-28R-alpha;IL-28RA;Likely interleukin or cytokine receptor 2;LICR2;IFNLR1;IL28RA;LICR2 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | IFNLR1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This IL28RA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 387-420 amino acids from the Central region of human IL28RA. |
| 计算分子量 | 58kDa |
| 成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity.The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG),which contribute to the antiviral state.Determines the cell type specificity of the lambda interferon action.Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory,gastrointestinal,and reproductive tracts.Seems not to be essential for early virus- activated host defense in vaginal infection,but plays an important role in Toll-like receptor (TLR)-induced antiviral defense.Plays a significant role in the antiviral immune defense in the intestinal epithelium. |
| Uniprot ID | Q8IU57 |
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