产品货号:
Z18638
中文名称:
HTR2A抗体
英文名称:
Anti-HTR2A Antibody (N-term)
产品规格:
80μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-HTR2A Antibody (N-term) |
指标别名 | 5-hydroxytryptamine receptor 2A;5-HT-2;5-HT-2A;Serotonin receptor 2A;Htr2a;Htr2 |
克隆性 | Polyclonal |
检验物种 | mouse |
应用范围 | WB,IHC |
基因名称 | Htr2a |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This Htr2a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 16-30 amino acids from the N-terminal region of human Htr2a. |
计算分子量 | 53kDa |
成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | G-protein coupled receptor for 5-hydroxytryptamine (serotonin).Also functions as a receptor for various drugs and psychoactive substances,including mescaline,psilocybin,1- (2,5- dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD).Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors.Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways.Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca (2+) ions from intracellular stores.Affects neural activity,perception,cognition and mood.Plays a role in the regulation of behavior,including responses to anxiogenic situations and psychoactive substances.Plays a role in intestinal smooth muscle contraction,and may play a role in arterial vasoconstriction. |
Uniprot ID | P35363 |
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