产品货号:
Z18622
中文名称:
HTR1A抗体
英文名称:
Anti-HTR1A Antibody (Center)
产品规格:
80μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-HTR1A Antibody (Center) |
指标别名 | 5 HT 1A;5 HT1A;5HT1a;ADRB2RL1;ADRBRL1;G 21;HTR1A;Serotonin receptor 1A |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,FCM |
基因名称 | HTR1A |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This HTR1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 239-273 amino acids from the Central region of human HTR1A. |
计算分子量 | 46kDa |
成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | G-protein coupled receptor for 5-hydroxytryptamine (serotonin).Also functions as a receptor for various drugs and psychoactive substances.Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors,such as adenylate cyclase.Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways.Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca (2+) ions from intracellular stores.Plays a role in the regulation of 5- hydroxytryptamine release and in the regulation of dopamine and 5- hydroxytryptamine metabolism.Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain,and thereby affects neural activity,mood and behavior.Plays a role in the response to anxiogenic stimuli. |
Uniprot ID | P08908 |
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