产品货号：
Z18620
中文名称：
IL4R抗体
英文名称：
Anti-IL4R Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IL4R Antibody |
| 指标别名 | CD124;IL 4 binding protein;IL 4 receptor subunit alpha;IL 4R alpha;IL 4R subunit alpha;IL 4RA;IL4 BP;IL4R;IL-4R;IL 4R;IL4RA;interleukin 4 receptor;sIL4Ralpha/prot;Soluble IL 4R alpha |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IHC |
| 基因名称 | IL4R |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human IL4R(219-232aa TKWHNSYREPFEQH). |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | IL4R(INTERLEUKIN 4 RECEPTOR) is a human gene that encodes the alpha chain of the interleukin-4 receptor,a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE antibody production in B cells.The IL4R gene is localized to 16p12.1-p11.2 by in situ hybridization and Southern blot analysis of DNA from a panel of mouse-human somatic cell lines.IL4 plays a major role in immunoglobulin E(IgE) production.Its signal is conferred to effector cells through binding to the alpha chain of the IL4 receptor.IL4 interacts with IL4R with high affinity,leading to dimerization with either the common gamma chain,a component of receptors for a number of cytokines,to create a type I receptor,or with IL13RA1 to form a type II receptor.The IL4R gene contains 12 exons and IL4R is a complex of at least 2 components,one of which is a novel affinity converting subunit that is critical for cellular signal transduction.See also IL13RA1 and IL13RA2. |
| Uniprot ID | P24394 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | interleukin 4 receptor |
| 蛋白名全称 | Interleukin-4 receptor subunit alpha(IL-4 receptor subunit alpha/IL-4R subunit alpha/IL-4R-alpha/IL-4RA) |
| 推荐稀释比 | Immunohistochemistry in paraffin section IHC-(P) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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