产品货号：
Z18562
中文名称：
IL6抗体
英文名称：
Anti-IL6 Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IL6 Antibody |
| 指标别名 | B cell stimulatory factor 2;BSF 2;BSF2;CDF;CTL differentiation factor;HSF;Hybridoma growth factor;IL 6;IL6;IL-6;Interferon beta 2;Interleukin 6 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IHC,WB |
| 基因名称 | IL6 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with mature length recombinant human IL-6 produced in E.coli. |
| 计算分子量 | 24kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2 |
| 纯化方式 | IL-6 antibody detects recombinant and native IL-6 present in body fluids and cell supernatants in various assays (ie.IL-1 stimulated IL-6 production from fibroblasts).In Western blot analysis of natural cell products or human body fluids,multiple bands of IL-6 will appear due to the variable amount of glycosylation on the molecule.The antiserum is also useful for neutralization of human of IL-6 activity in bioassays.For neutralization,incubate the sample with a 1:400 dilution of the antiserum for at least 4hours before being tested.A control of similarly diluted normal rabbit IgG (heat inactivated) is recommended.In neutralization experiments in vitro,this antibody does not result in enhanced activity of IL-6.However,because antibodies to IL-6 may act as a soluble receptor in vivo,some antibodies to IL-6 act as carriers and enhance IL-6 activity.This product has minimal reactivity with mouse IL-6. |
| 浓度 | 1.0mg/mL by UV absorbance at 280nm |
| 产品形态 | Lyophilized |
| 保存条件 | Store vial at 4℃ prior to restoration.For extended storage aliquot contents and freeze at -20℃ or below.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | Anti-IL-6 antibody is validated by ELISA,Immunohistochemistry and Western Blot Assays.IL-6 is a secreted cytokine with a wide variety of biological functions.It is a potent inducer of the acute phase response and plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation.IL-6 induces myeloma and plasmacytoma growth and induces nerve cells differentiation and acts on B-cells,T-cells,hepatocytes,hematopoeitic progenitor cells and cells of the CNS.IL-6 also acts as a myokine.It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. |
| Uniprot ID | P05231 |
| 推荐稀释比 | ELISA:1:10,000 IHC:1:200 - 1:1,000 WB:1:300 - 1:1,000 |
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