产品货号：
Z18393
中文名称：
Integrin alpha 8/ITGA8抗体
英文名称：
Anti-Integrin alpha 8/ITGA8 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Integrin alpha 8/ITGA8 Antibody |
| 指标别名 | ITGA8;Integrin alpha-8;Integrin alpha-8 heavy chain;Integrin alpha-8 light chain |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,ICCIF,FCM,ELISA |
| 基因名称 | ITGA8 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human ITGA8 recombinant protein (Position:E347-D964). |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Integrin alpha-8 is a protein that in humans is encoded by the ITGA8 gene.Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion,cytoskeletal rearrangement,and activation of cell signaling pathways.Integrins are composed of alpha and beta subunits.This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein.The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats.This repeat is predicted to fold into a beta propeller structure.This gene regulates the recruitment of mesenchymal cells into epithelial structures,mediates cell-cell interactions,and regulates neurite outgrowth of sensory and motor neurons.The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis.Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease.Alternate splicing results in multiple transcript variants encoding distinct isoforms. |
| Uniprot ID | P53708 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for ICC. |
| 基因名全称 | integrin subunit alpha 8 |
| 蛋白名全称 | Integrin alpha-8 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 |
| Gene ID | 8516 |
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