产品货号：
Z18332
中文名称：
IQSEC1抗体
英文名称：
Anti-IQSEC1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IQSEC1 Antibody |
| 指标别名 | IQ motif and Sec7 domain 1,ADP-ribosylation factors guanine nucleotide-exchange protein 100,ARFGEP100,BRAG2,Brefeldin-resistant Arf-GEF 2 protein |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | IQSEC1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | IQSEC1 antibody was raised against a 19 amino acid peptide near the amino terminus of human IQSEC1.The immunogen is located within amino acids 60 - 110 of IQSEC1. |
| 计算分子量 | 108kDa |
| 成分 | IQSEC1 antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | IQSEC1 antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | ADP ribosylation factors (Arfs) are small GTP-binding proteins known for their role in vesicular transport,where they nucleate the assembly of coat protein complexes at sites of carrier vesicle formation.IQSEC1 (GEP100/BRAG2),a guanine nucleotide exchange protein for ARF6,belongs to the BRAG family and contains one IQ domain,one PH domain and one SEC7 domain (1).As a known activator of ARF6,IQSEC1 regulates cell surface levels of Beta1 integrin and its knockdown blocked tumour metastasis (2,3).IQSEC1 links EGFR signaling to ARF6 activation and may contribute to the cancer metastasis and malignancy (4). |
| Uniprot ID | Q6DN90 |
| 基因名全称 | IQ motif and Sec7 domain 1 |
| 蛋白名全称 | IQ motif and Sec7 domain 1 |
| 推荐稀释比 | IQSEC1 antibody can be used for detection of IQSEC1 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunocytochemistry at 2μg/mL.For immunofluorescence start at 2μg/mL.Antibody validated:Western Blot in mouse samples;Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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