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产品目录

IL-17/IL17A抗体图片
产品货号:
Z18289
中文名称:
IL-17/IL17A抗体
英文名称:
Anti-IL-17/IL17A Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-IL-17/IL17A Antibody
指标别名CTLA 8;CTLA8;IL 17;IL 17A;IL17;IL-17;IL17A;interleukin 17A
克隆性Polyclonal
检验物种human
应用范围IHC
基因名称IL17A
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence of human IL17A (EDPERYPSVIWEAKCRH).
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Interleukin-17A is a protein that in humans is encoded by the IL17A gene.This gene is a member of the IL-17 receptor family which includes five members (IL-17RA-E) and the encoded protein is a proinflammatory cytokine produced by activated T cells.IL-17A-mediated downstream pathways induce the production of inflammatory molecules,chemokines,antimicrobial peptides,and remodeling proteins.The encoded protein elicits crucial impacts on host defense,cell trafficking,immune modulation,and tissue repair,with a key role in the induction of innate immune defenses.This cytokine stimulates non-hematopoietic cells and promotes chemokine production thereby attracting myeloid cells to inflammatory sites.This cytokine also regulates the activities of NF-kappaB and mitogen-activated protein kinases and can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2),as well as enhance the production of nitric oxide (NO).IL-17A plays a pivotal role in various infectious diseases,inflammatory and autoimmune disorders,and cancer.High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis,psoriasis and multiple sclerosis.The lung damage induced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is to a large extent,a result of the inflammatory response promoted by cytokines such as IL17A
Uniprot IDQ16552
推荐配套试剂Biorab recommends HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).
基因名全称interleukin 17A
蛋白名全称Interleukin-17A
推荐稀释比
Immunohistochemistry in paraffin section (IHC) 1:50~400
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:IL-17/IL17A抗体IL-17抗体IL17A多抗Anti-IL-17/IL17A Antibody
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