产品货号:
Z18079
中文名称:
ILP-2/BIRC8抗体
英文名称:
Anti-ILP-2/BIRC8 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ILP-2/BIRC8 Antibody |
指标别名 | ILP2,ILP-2,hILP2,ILP2,Baculoviral IAP repeat-containing protein 8,Inhibitor of apoptosis-like protein 2,IAP-like protein 2 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,ICC,IF |
基因名称 | BIRC8 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | ILP-2 antibody was raised with against a synthetic peptide corresponding to amino acids near the amino terminus of human ILP-2.The immunogen is located within the first 50 amino acids of ILP-2. |
计算分子量 | 27kDa |
成分 | ILP-2 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | ILP-2 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Apoptosis,or programmed cell death,is related to many diseases,such as cancer.Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins.IAP proteins form a conserved gene family including IAP,XIAP/ILP-1/MIHA,and Livin/KIAP that bind to and inhibits specific proteases.A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2.ILP-2 has high homology to ILP-1,but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues.ILP-2,unlike ILP-1,has no inhibitory effect on Fas and TNF induced apoptosis,but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1.ILP-2 interacts with the processed caspase-9.These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9. |
Uniprot ID | Q96P09 |
基因名全称 | Baculoviral IAP repeat-containing 8 |
蛋白名全称 | Baculoviral IAP repeat-containing 8 |
推荐稀释比 | ILP-2 antibody can be used for detection of ILP-2 by Western blot at 1μg/mL.A band at approximately 33kDa can be detected.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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