产品货号：
Z18079
中文名称：
ILP-2/BIRC8抗体
英文名称：
Anti-ILP-2/BIRC8 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ILP-2/BIRC8 Antibody |
| 指标别名 | ILP2,ILP-2,hILP2,ILP2,Baculoviral IAP repeat-containing protein 8,Inhibitor of apoptosis-like protein 2,IAP-like protein 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | BIRC8 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ILP-2 antibody was raised with against a synthetic peptide corresponding to amino acids near the amino terminus of human ILP-2.The immunogen is located within the first 50 amino acids of ILP-2. |
| 计算分子量 | 27kDa |
| 成分 | ILP-2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ILP-2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Apoptosis,or programmed cell death,is related to many diseases,such as cancer.Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins.IAP proteins form a conserved gene family including IAP,XIAP/ILP-1/MIHA,and Livin/KIAP that bind to and inhibits specific proteases.A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2.ILP-2 has high homology to ILP-1,but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues.ILP-2,unlike ILP-1,has no inhibitory effect on Fas and TNF induced apoptosis,but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1.ILP-2 interacts with the processed caspase-9.These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9. |
| Uniprot ID | Q96P09 |
| 基因名全称 | Baculoviral IAP repeat-containing 8 |
| 蛋白名全称 | Baculoviral IAP repeat-containing 8 |
| 推荐稀释比 | ILP-2 antibody can be used for detection of ILP-2 by Western blot at 1μg/mL.A band at approximately 33kDa can be detected.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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