产品货号:
Z18045
中文名称:
HER2/ERBB2抗体
英文名称:
Anti-HER2/ERBB2 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-HER2/ERBB2 Antibody |
指标别名 | CD340;ERBB2;HER 2;HER 2/neu;HER2;MLN 19;MLN19;NEU;NGL;p185;p185erbB2;Proto oncogene c ErbB 2;Proto oncogene Neu;TKR1 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,IHC,FCM,ELISA |
基因名称 | ERBB2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human HER2/ERBB2 recombinant protein (Position:A980-R1230). |
实际分子量 | 185KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Receptor tyrosine-protein kinase erbB-2,also known as CD340 (cluster of differentiation 340),proto-oncogene Neu,Erbb2 (rodent),or ERBB2 (human),is a protein that in humans is encoded by the ERBB2 gene.And it is also frequently called HER2 (from human epidermal growth factor receptor 2) or HER2/neu.This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases.This protein has no ligand binding domain of its own and therefore cannot bind growth factors.Amplification and/or overexpression of this gene has been reported in numerous cancers,including breast and ovarian tumors.Alternative splicing results in several additional transcript variants,some encoding different isoforms and others that have not been fully characterized. |
Uniprot ID | P04626 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
基因名全称 | erb-b2 receptor tyrosine kinase 2 |
蛋白名全称 | Receptor tyrosine-protein kinase erbB-2 |
推荐稀释比 | Western blot(WB) 1:500~2000 (ELISA): 1:100~1000 Flow cytometry (FCM) 1~3μg/1×106 cells Immunohistochemistry in paraffin section (IHC) 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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