产品货号：
Z18018
中文名称：
HLA-DMB抗体
英文名称：
Anti-HLA-DMB Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HLA-DMB Antibody |
| 指标别名 | D6S221E;DMB;HLA DMB;HLA-DMB;MHC class II antigen DMB;RING7 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | HLA-DMB |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human HLA DMB(81-100aa NQKDTLMQRLRNGLQNCATH). |
| 实际分子量 | 29KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | HLA-DMB(major histocompatibility complex,class II,DM beta),also known as D6S221E,RING7,HLA-DM histocompatibility type,beta chain,HLADMB or RING7,is a protein that in humans is encoded by the HLA-DMB gene.The HLA-DMB gene is mapped on 6p21.32.HLA-DMB belongs to the HLA class II beta chain paralogues.This class II molecule is a heterodimer consisting of an alpha(DMA) and a beta(DMB) chain,both anchored in the membrane.It is located in intracellular vesicles.DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP(class II-associated invariant chain peptide) molecule from the peptide binding site.Class II molecules are expressed in antigen presenting cells.The beta chain is approximately 26～28kDa and its gene contains 6 exons.HLA-DMA and -DMB appear to encode subunits of a functional heterodimer that is critical in the pathway of class II antigen presentation. |
| Uniprot ID | P28068 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | major histocompatibility complex,class II,DM beta |
| 蛋白名全称 | HLA class II histocompatibility antigen,DM beta chain |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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