产品货号：
Z17981
中文名称：
HIF-1 alpha/HIF1A抗体
英文名称：
Anti-HIF-1 alpha/HIF1A Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HIF-1 alpha/HIF1A Antibody |
| 指标别名 | ARNT interacting protein;bHLHe78;HIF 1 alpha;HIF 1alpha;HIF1;HIF-1;HIF1 ALPHA;HIF1A;HIF-1α;Member of PAS protein 1;MOP1;PASD8 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | HIF1A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminal of human HIF-1-alpha (703-732aa EEELNPKILALQNAQRKRKMEHDGSLFQAV),different from the related mouse and rat sequences by three amino acids. |
| 实际分子量 | 120KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | HIF-1α (Hypoxia-inducible factor 1α,HIF1A) is a transcription factor that mediates cellular and systemic homeostatic responses to reduced O2 availability in mammals,including angiogenesis,erythropoiesis and glycolysis.This gene was mapped to 14q21-q24.HIF-1α transactivate genes required for energy metabolism and tissue perfusion and is necessary for embryonic development and tumor explant growth.HIF-1alpha is over expressed during carcinogenesis,myocardial infarction and wound healing.It is crucial for the cellular response to hypoxia and is frequently over expressed in human cancers,resulting in the activation of genes essential for cell survival.HIF-1α regulates the survival and function in the inflammatory microenvironment directly.It is a transcription factor that plays a pivotal role in cellular adaptation to changes in oxygen availability. |
| Uniprot ID | Q16665 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | hypoxia inducible factor 1,alpha subunit (basic helix-loop-helix transcription factor) |
| 蛋白名全称 | Hypoxia-inducible factor 1-alpha |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：HIF-1 alpha/HIF1A抗体，HIF-1 alpha抗体，HIF1A多抗，Anti-HIF-1 alpha/HIF1A Antibody