
产品货号:
Z17967
中文名称:
HINT1抗体
英文名称:
Anti-HINT1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-HINT1 Antibody |
指标别名 | HINT;HINT1;PKCI 1;PKCI1;PRKCNH1;Protein kinase C inhibitor 1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,ICC |
基因名称 | HINT1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | HINT1 antibody was raised against a 17 amino acid synthetic peptide near the center of the human HINT1.The immunogen is located within the last 50 amino acids of HINT1. |
计算分子量 | 14kDa |
成分 | HINT1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | HINT1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Histidine triad nucleotide-binding protein 1 (HINT1) is a member of the histidine triad (HIT) protein family,a group of small nucleotide-binding and -hydrolyzing proteins.HINT1 interacts with several diverse proteins and has been suggested to have tumor suppressive activities.HINT1 catalyzes the hydrolysis of adenosine 5'-monophoramidate substrates such as AMP-morpholidate,but its enzymatic function does not appear to play a role in its tumor suppression.Recent experiments demonstrate that HINT1 forms a complex with POSH and JNK in vivo,inhibiting AP-1 activity and the phosphorylation of c-Jun,and this action could contribute to the tumor suppressor activity of HINT1.Other studies raise the possibility of HINT1 as a candidate gene for schizophrenia. |
Uniprot ID | P49773 |
基因名全称 | Histidine triad nucleotide binding protein 1 |
蛋白名全称 | Histidine triad nucleotide binding protein 1 |
推荐稀释比 | HINT1 antibody can be used for detection of HINT1 by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunocytochemistry starting at 2.5μg/mL.Antibody validated:Western Blot in human samples and Immunocytochemistry in human samples.All other applications and species not yet tested. |
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