产品货号:
Z17731
中文名称:
HDAC5 (internal)抗体
英文名称:
Anti-HDAC5 (internal) Antibody
产品规格:
100μg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-HDAC5 (internal) Antibody |
指标别名 | Antigen NY CO 9;HD5;HDAC5;histone deacetylase 5;KIAA0600;NY CO 9 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | Dot blot,ELISA,WB |
基因名称 | HDAC5 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | HDAC5 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the internal region surrounding phosphoserine 661 of human HDAC5. |
计算分子量 | 122kDa |
成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,50% (v/v) Glycerol |
纯化方式 | Anti-HDAC5 was affinity purified from monospecific antiserum by immunoaffinity chromatography.This antibody is specific towards HDAC5.A BLAST analysis was used to suggest cross-reactivity with Human based on 100% sequence homology.Cross-reactivity with HDAC5 from other sources has not been determined. |
浓度 | 1.12mg/mL by UV absorbance at 280nm |
产品形态 | 溶液 |
保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is six (6) months from date of opening. |
背景资料 | HDAC5 is a member of the class II mammalian histone deacetylase family,which is structurally related to yeast HDA1.Human HDAC5 is composed of 1122 amino acid residues.The deacetylase domain of HDAC5 is located at the C-terminal half of the molecule.The N-terminal non-deacetylase domain does not show any significant homology with any published sequence.Both domains are required for HDAC5-mediated repression of gene transcription.HDAC5 interacts with a growing number of transcriptional factors including MEF2A as well as other HDAC proteins.The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions.Anti-HDAC5 antibodies are ideal for researchers interested in Breast Cancer,Cancer,Cell Cycle and Replication,Chromatin Research,Epigenetics,and Histone Deacetylases research. |
Uniprot ID | Q9UQL6 |
基因名全称 | Histone deacetylase 5 |
推荐稀释比 | ELISA:1:20,000 - 1:60,000 IHC:1:100~1:500 IF Microscopy:1:100~1:500 WB:0.2μg/mL |
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