产品货号：
Z17698
中文名称：
Glucocorticoid receptor/NR3C1抗体
英文名称：
Anti-Glucocorticoid receptor/NR3C1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Glucocorticoid receptor/NR3C1 Antibody |
| 指标别名 | GCCR;GCR;Glucocorticoid receptor;GR;GRL;NR3C1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | NR3C1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human NR3C1 recombinant protein (Position:M1-D373).Human NR3C1 shares 85% and 82% amino acid (aa) sequences identity with mouse and rat NR3C1,respectively. |
| 实际分子量 | 100KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The glucocorticoid receptor (GR,or GCR),also known as NR3C1,is the receptor to which cortisol and other glucocorticoids bind.In humans,the GR protein is encoded by NR3C1 gene which is located on chromosome 5 (5q31).GR is expressed in almost every cell in the body and regulates genes controlling the development,metabolism,and immune response.Because the receptor gene is expressed in several forms,it has many different (pleiotropic) effects in different parts of the body.The activated GR complex up-regulates the expression of anti-inflammatory proteins in the nucleus or represses the expression of pro-inflammatory proteins in the cytosol (by preventing the translocation of other transcription factors from the cytosol into the nucleus). |
| Uniprot ID | P04150 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | nuclear receptor subfamily 3,group C,member 1 (glucocorticoid receptor) |
| 蛋白名全称 | Glucocorticoid receptor |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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