产品货号：
Z17681
中文名称：
HDAC11抗体
英文名称：
Anti-HDAC11 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HDAC11 Antibody |
| 指标别名 | histone deacetylase 11;HD11;HDAC11 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | HDAC11 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC11 (47-81aa NFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLN),different from the related mouse sequence by one amino acid. |
| 实际分子量 | 37KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Histone deacetylase 11 is a 39kDa histone deacetylase enzyme that in humans is encoded by the HDAC11 gene on chromosome 3 in humans and chromosome 6 in mice.This gene encodes a class IV histone deacetylase.And the encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10.Alternative splicing results in multiple transcript variants.HDAC11 expression is normally found in brain and testis tissue,but upregulation of HDAC11 expression has also been seen in various cancer cells.In addition,HDAC11 has been shown to be a negative regulator of IL-10 production in antigen presenting cells.It has also been shown that inhibition of HDAC11 results in increased expression of OX40L in Hodgkin lymphoma cells. |
| Uniprot ID | Q96DB2 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | histone deacetylase 11 |
| 蛋白名全称 | Histone deacetylase 11 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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