产品货号：
Z17664
中文名称：
HDAC1 (near C-terminus)抗体
英文名称：
Anti-HDAC1 (near C-terminus) Antibody
产品规格：
25μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HDAC1 (near C-terminus) Antibody |
| 指标别名 | GON 10;HD1;HDAC1;histone deacetylase 1;RPD3;RPD3L1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,IF,IHC,WB |
| 基因名称 | HDAC1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Anti-HDAC-1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a C-Terminal region near amino acids 450-482 of Human HDAC-1. |
| 计算分子量 | 55kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.1% (w/v) Sodium Azide |
| 纯化方式 | Anti-HDAC-1 antibody is directed against human HDAC-1 protein.HDAC-1 antibody was affinity purified from monospecific antiserum by immunoaffinity purification.A BLAST analysis was used to suggest reactivity with this protein from human,mouse,rat and chimpanzee sources based on 100% homology for the immunogen sequence.Cross-reactivity may occur with HDAC-1 from bovine (82% homology) and chicken (80% homology) sources.Cross-reactivity with HDAC-1 homologues from other sources has not been determined. |
| 浓度 | 1.0mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ or below prior to opening.This vial contains a relatively low volume of reagent (25μL).To minimize loss of volume dilute 1:10 by adding 225μL of the buffer stated above directly to the vial.Recap,mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial.Use this intermediate dilution when calculating final dilutions as recommended below.Store the vial at -20℃ or below after dilution.Avoid cycles of freezing and thawing.Expiration date is one (1) year from date of opening. |
| 背景资料 | HDAC-1 antibody recognizes HDAC1 (also known as HD1,histone deacetylase 1,RPD3,RPD3L1) which belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex.Histone acetylation and deacetylation,catalyzed by multisubunit complexes,play a key role in the regulation of eukaryotic gene expression.It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation.Together with metastasis-associated protein-2,it deacetylates p53 and modulates its effect on cell growth and apoptosis. |
| Uniprot ID | Q13547 |
| 基因名全称 | Histone deacetylase 1 |
| 蛋白名全称 | Histone deacetylase 1 |
| 推荐稀释比 | ELISA:1:10,000 - 1:50,000 IHC:1:200 - 1:1,000 IF Microscopy:10μg/mL WB:1:1,000 - 1:5,000 |
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