产品货号:
Z17540
中文名称:
GAD1抗体
英文名称:
Anti-GAD1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-GAD1 Antibody |
指标别名 | GAD;GAD 67;GAD1;GAD67;Glutamate decarboxylase 1;SCP |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | GAD1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human GAD67 recombinant protein (Position:N14-D122).Human GAD67 shares 95% amino acid (aa) sequence identity with both mouse and rat GAD67. |
实际分子量 | 67KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Glutamate decarboxylase 1 (brain,67kDa) (GAD67),also known as GAD1,is a human gene.It is mapped to 2q31.1.This gene encodes one of several forms of glutamic acid decarboxylase,identified as a major autoantigen in insulin-dependent diabetes.The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid.A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes.This gene may also play a role in the stiff man syndrome.Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures.Alternative splicing of this gene results in two products,the predominant 67-kD form and a less-frequent 25-kD form. |
Uniprot ID | Q99259 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | glutamate decarboxylase 1 (brain,67kDa) |
蛋白名全称 | Glutamate decarboxylase 1 |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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