产品货号：
Z17428
中文名称：
GLE1抗体
英文名称：
Anti-GLE1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GLE1 Antibody |
| 指标别名 | GLE1;GLE1 like protein;GLE1L;hGLE1;LCCS;LCCS1;Nucleoporin GLE1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | GLE1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Gle1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human Gle1.The immunogen is located within amino acids 540 - 590 of Gle1. |
| 计算分子量 | 80kDa |
| 成分 | Gle1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Gle1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The proper expression of gene products in eukaryotic cells relies on efficient transport of mRNA molecules out of the nucleus.Gle1 is an essential mRNA export factor in both human and yeast cells.It associates with the nuclear pore complex (NPC) through hCG1 and NUP155 in mammalian cells and in conjunction with inositol hexakisphosphate (IP6),stimulates Dbp5,a member of the DEAD-box helicase family,triggering mRNP remodeling and facilitating RNA export from the nucleus.Recent evidence suggests that mutations in Gle1 causing defects in mRNA export can result in human disease.At least three isoforms of Gle1 are known to exist. |
| Uniprot ID | Q53GS7 |
| 基因名全称 | GLE1 RNA export mediator homolog (yeast) |
| 蛋白名全称 | GLE1 RNA export mediator homolog (yeast) |
| 推荐稀释比 | Gle1 antibody can be used for detection of Gle1 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 5μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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