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产品目录

所在位置:所有产品 > 抗体抗原 > 一抗 > HDAC8抗体
HDAC8抗体图片
产品货号:
Z17399
中文名称:
HDAC8抗体
英文名称:
Anti-HDAC8 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-HDAC8 Antibody
指标别名HD8;HDAC8;HDACL1;histone deacetylase 8;RPD3
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB,IHC
基因名称HDAC8
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC8(18-33aa YIYSPEYVSMCDSLAK),different from the related mouse and rat sequences by two amino acids.
实际分子量42KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料HDAC8,Histone deacetylase 8,is an enzyme that in humans is encoded by the HDAC8 gene,and is biologically involved in skull morphogenesis and metabolic control of the ERR-alpha/PGC1-alpha transcriptional complex.Sequence analysis predicted that the 377-amino acid HDAC8 protein contains the 9 conserved HDAC blocks that are presumably important for catalytic function.HDAC8 shares 54% sequence similarity with HDAC1 and HDAC2 and 39% similarity with HDAC3,making it a class I HDAC.Histones play a critical role in transcriptional regulation,cell cycle progression,and developmental events.Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family.It has histone deacetylase activity and represses transcription when tethered to a promoter.
Uniprot IDQ9BY41
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称histone deacetylase 8
蛋白名全称Histone deacetylase 8(HD8)
推荐稀释比
Western blot(WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:HDAC8抗体HDAC8多抗Anti-HDAC8 Antibody
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