产品货号：
Z17386
中文名称：
HDC抗体
英文名称：
Anti-HDC Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HDC Antibody |
| 指标别名 | HDC;Histidine decarboxylase |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | HDC |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Histidine decarboxylase/HDC recombinant protein (Position:R12-V662). |
| 实际分子量 | 74KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | HDC(Histidine decarboxylase) is the enzyme that catalyzes the reaction that produces histamine from histidine with the help of vitamin B6.The HDC gene is mapped on 15q21.2.The deduced 662-amino acid protein has a molecular mass of 74,148 Da.The gene contains 12 exons spanning approximately 24kb.The biogenic amine histamine is an important modulator of numerous physiologic processes,including neurotransmission,gastric acid secretion,and smooth muscle tone.The biosynthesis of histamine from histidine is catalyzed by the enzyme L-histidine decarboxylase.This homodimeric enzyme is a pyridoxal phosphate(PLP)-dependent decarboxylase and is highly specific for its histidine substrate.Ercan-Sencicek et al.noted that animal studies had shown that lack of Hdc in mice results in increased locomotor and stereotypic behaviors,as well as increased anxiety. |
| Uniprot ID | P19113 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | histidine decarboxylase |
| 蛋白名全称 | Histidine decarboxylase |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 ELISA： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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