产品货号：
Z17318
中文名称：
GRP75/HSPA9抗体
英文名称：
Anti-GRP75/HSPA9 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GRP75/HSPA9 Antibody |
| 指标别名 | CSA;GRP 75;GRP75;Heat shock 70kDa protein 9;HSPA9;HSPA9B;Mortalin;MOT;mot 2;MOT2;MTHSP75;PBP74;Peptide binding protein 74 |
| 克隆性 | Polyclonal |
| 检验物种 | human,monkey,mouse |
| 应用范围 | WB,IHC,FCM |
| 基因名称 | HSPA9 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human Grp75 (646-679aa KLFEMAYKKMASEREGSGSSGTGEQKEDQKEEKQ),identical to the related mouse and rat sequences. |
| 实际分子量 | 74KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | HSPA9 (heat shock 70kDa protein 9 (mortalin)),also known as GRP75,mot-2,mthsp75,PBP74,HSPA9B,MORTALIN or MORTALIN,PERINUCLEAR,is a highly conserved member of the HSP70 family of proteins.It functions as a chaperone in the mitochondria,cytoplasm,and centrosome.The HSPA9 gene is mapped to chromosome 5q31.2 based on an alignment of the HSPA9 sequence with the genomic sequence.Knockdown of HSPA9 in erythroid cultures was associated with an increased number of cells in the G0/G1 phase of the cell cycle and accelerated apoptosis.Knockdown of Hspa9 in mouse bone marrow cells,followed by transplantation into wildtype recipients,also resulted in loss of erythroid cell number.Haploinsufficiency for HSPA9 may contribute to abnormal hematopoiesis in myelodysplastic syndromes.This protein plays a role in the control of cell proliferation. |
| Uniprot ID | P38646 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | heat shock 70kDa protein 9 (mortalin) |
| 蛋白名全称 | Stress-70 protein,mitochondrial |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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