产品货号：
Z17315
中文名称：
GRP78/BIP/HSPA5抗体
英文名称：
Anti-GRP78/BIP/HSPA5 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GRP78/BIP/HSPA5 Antibody |
| 指标别名 | BIP;GRP 78;GRP78;GRP78/BIP;HSP A5;HSPA5;MIF2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat,rabbit |
| 应用范围 | IHC |
| 基因名称 | HSPA5 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human GRP78 BiP(603-617aa EWLESHQDADIEDFK),identical to the related mouse and rat sequences. |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | HSPA5(heat shock 70kDa protein 5) also known as glucose-regulated protein,78kD(GRP78) or BiP,is a member of the heat-shock protein-70(HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum.BiP is also an essential component of the translocation machinery,as well as playing a role in retrograde transport across the ER membrane of aberrant proteins destined for degradation by the proteasome.The HSPA5 gene is mapped on 9q33.3.Shen et al.(2002)°Concluded that HSPA5 retains ATF6 in the ER by inhibiting its Golgi localization signals and that dissociation of HSPA5 during ER stress allows ATF6 to be transported to the Golgi.The findings of Shen et al.(2002) demonstrated that HSPA5 is a key element in sensing the folding capacity within the ER. |
| Uniprot ID | P11021 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | heat shock 70kDa protein 5(glucose-regulated protein,78kDa) |
| 蛋白名全称 | 78kDa glucose-regulated protein |
| 推荐稀释比 | Immunohistochemistry in paraffin section IHC-(P) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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