产品货号:
Z17306
中文名称:
GRK6抗体
英文名称:
Anti-GRK6 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-GRK6 Antibody |
指标别名 | GPRK6;GRK6 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | GRK6 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | GRK6 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human GRK6.The immunogen is located within the last 50 amino acids of GRK6. |
计算分子量 | 66kDa |
成分 | GRK6 antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | GRK6 antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | The G protein每coupled receptor kinases (GRKs) are a versatile family of kinases that play a critical role in cancer metastasis through their regulation of G-protein coupled receptors (GPCRs) involved in growth factor mediated cell migration (1,2).Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state (1).GRK6 is one of 7 members of the GRK serine/threonine kinase subfamily,which has been shown to modulate the Wnt signaling pathway via phosphorylation of LRP6 (3,4),and the insulin-like growth factor signaling pathway (4).GRK6 may also play a role in immune system function (5). |
Uniprot ID | P43250 |
基因名全称 | G protein-coupled receptor kinase 6 |
蛋白名全称 | G protein-coupled receptor kinase 6 |
推荐稀释比 | GRK6 antibody can be used for detection of GRK6 by Western blot at 1 ~ 2μg/mL.Antibody can also be used for Immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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