产品货号：
Z17298
中文名称：
FKBP15抗体
英文名称：
Anti-FKBP15 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FKBP15 Antibody |
| 指标别名 | FKBP15;KIAA0674;FKBP-15;133kDa FK506-binding protein;133kDa FKBP;FKBP-133;WASP- and FKBP-like protein;WAFL |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | FKBP15 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human FKBP135/FKBP15 recombinant protein (Position:A19-D1210). |
| 实际分子量 | 160KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | FKBP15,also known as FKBP133,is a member of the FK506-binding protein family,a group of proteins initially identified as immunophilins,targets for the immunosupressant drugs FK506 and Rapamycin.FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif.FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons;overexpression of FKBP15 resulted in the number of filopodia in transfected neurons,suggesting that FKBP15 modulates growth cone behavior.FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes.At least three isoforms of FKBP15 are known to exist. |
| Uniprot ID | Q5T1M5 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | FKBP prolyl isomerase family member 15 |
| 蛋白名全称 | FK506-binding protein 15 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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