产品货号:
Z17297
中文名称:
FKBP15抗体
英文名称:
Anti-FKBP15 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-FKBP15 Antibody |
指标别名 | FKBP15;KIAA0674;FKBP-15;133kDa FK506-binding protein;133kDa FKBP;FKBP-133;WASP- and FKBP-like protein;WAFL |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | FKBP15 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | FKBP15 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human FKBP15.The immunogen is located within amino acids 30 - 80 of FKBP15. |
计算分子量 | 134kDa |
成分 | FKBP15 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | FKBP15 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | FKBP15,also known as FKBP133,is a member of the FK506-binding protein family,a group of proteins initially identified as immunophilins,targets for the immunosupressant drugs FK506 and Rapamycin.FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif.FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons;overexpression of FKBP15 resulted in the number of filopodia in transfected neurons,suggesting that FKBP15 modulates growth cone behavior.FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes.At least three isoforms of FKBP15 are known to exist. |
Uniprot ID | Q5T1M5 |
基因名全称 | FK506 binding protein 15,133kDa |
蛋白名全称 | FK506 binding protein 15,133kDa |
推荐稀释比 | FKBP15 antibody can be used for detection of FKBP15 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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